Table 1 SPT results to various concentrations of nPru p 3, levels of serum specific IgE, IgG, IgG₁ and IgG₄ against nPru p 3, and DBPCFC before SLIT, and at the 4^th, 8^th and 12^th month of active treatment

T = 0

T = 4 months

T = 8 months

T = 12 months

Histamine

6

6

7

8

nPru p 3 1 µg/ml

3

3

2

2

nPru p 3 10 µg/ml

6

4

3

2

nPru p 3 100 µg/ml

12

5

4

3

nPru p 3 500 µg/ml

14

6

5

4

sIg levels

sIgE Pru p 3 (kU/L)

1.8

1.7

1.2

1.9

sIgG Pru p 3*

0.76

0.94

0.84

0.76

sIgG1 Pru p 3**

0.60

0.74

0.71

0.62

sIgG4 Pru p 3**

0.83

1.01

1.04

0.75

DBPCFC

Positive

Negative

Negative

Negative