Skip to main content

Table 1 Differentiating features of RS3PE Syndrome and PMR

From: Acute onset polyarthritis in older people: Is it RS3PE syndrome?

RS3PE Syndrome

PMR

Dramatic response to low dose steroids or NSAIDS and sometimes to hydroxychloroquine.

Responds only to steroids

Common in males

More frequent in females

Mainly involves wrist with pitting oedema.

Involves shoulder and pelvic girdle with associated systemic symptoms. Pitting oedema present rarely.

Association with HLA-B7, B27, A2

HLA association with HLA-DR4

Excellent long-term prognosis

Frequent relapses and recurrences.