From: Primary osteogenic sarcoma of the breast: A case report
 | Learning points |
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1. | Primary breast sarcomas are rare tumours of the breast. They make up less than 0.1% of all breast tumours. |
2. | Tumour development is either from normal breast tissue de novo, or as metaplastic differentiation of a primary benign or malignant breast lesion. Secondary deposits from a primary bone sarcoma occur only rarely, but need to be |
3. | excluded clinically. Diagnosis is made by careful assessment of the histological specimen, together with immunohistochemical staining. |
4. | Typically primary osteogenic breast cancer is usually considered a poor prognosis tumour, with high risk of disease recurrence and haematogeneous spread, most commonly to the lungs. Lymph node metastases do not occur. |