Table 1 Immunohistochemical staining pattern in the present case
From: Carcinoma developing in ectopic pancreatic tissue in the stomach: a case report
Antibody | Gastric tumor site | Gastric heterotopic pancreas site | Description & use of antibody |
CEA | (+) | (++) | Oncofetal antigen in gastrointestinal, breast, lung, pancreas and other cancers. |
CA 19-9 | (-) | (-) | Useful cerum marker in gastrointestinal and pancreatic cancer; strongest staining in pancreatic cancer. |
Cytokeratin 7 | (+) | (++) | Typically found in simple epithelia from the GI tract; lesser degree of expression in gastric cancer. |
Cytokeratin 19 | (+) | (-) | Cytokeratin filament in a large number of epithelial cell types, including many ductal and glandular epithelia. |
Cytokeratin 20 | (±) | (-) | Restricted expression in intestinal epithelium, gastric foveolar epithelium and others; lesser degree of expression in pancreatic cancer. |
MUC1 | (-) | (+) | Glycoprotein of glandular epithelial tissues; modifications to glycosylation of musins in cancer; "gastric mucin" & "PanINs mucin". |
Ki-67 | (++) | (-) | The assessment of cell proliferation in neoplastic cell populations |