TY - JOUR AU - Brostoff, Joshua M. AU - Rashid, Sukaina AU - McCrea, Daniel PY - 2008 DA - 2008/07/14 TI - Primary Biliary Cirrhosis with a normal Alkaline Phosphatase: a case report JO - Cases Journal SP - 33 VL - 1 IS - 1 AB - A 78 year-old lady presented with abdominal swelling and fatigue. She was anaemic with mild hypoalbuminaemia, and had a normal alkaline phosphatase. Computed tomography showed hepatosplenomegaly and mild ascites. Anti mitochondrial antibodies were strongly positive, as were anti nuclear antibodies, and the gamma glutamyl-transferase was shown to be elevated. A diagnosis of primary biliary cirrhosis was made. A brief discussion of treatment of primary biliary cirrhosis follows. The case is notable for the fact that primary biliary cirrhosis can manifest clinically without an elevation in alkaline phosphatase – normally the hallmark of the disease. SN - 1757-1626 UR - https://doi.org/10.1186/1757-1626-1-33 DO - 10.1186/1757-1626-1-33 ID - Brostoff2008 ER -