Figure 1

Imatinib causes elevated liver transaminases. Temporal relationship of imatinib therapy with markedly elevated ALT and AST levels secondary to hepatic hemosiderosis. The concurrently elevated serum ferritin level and the time of initiation of treatment with phlebotomy are indicated. Patient was on imatinib 400-600 mg daily during the whole period of time except a brief discontinuation of 2 weeks in the second month due to neutropenic fever. The dosage of imatinib is indicated. The break in the line indicates the 2-week period during which imatinib was discontinued for neutropenic fever.