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Table 3 Draft ICD-10 criteria for CRF.

From: Mistletoe treatment in cancer-related fatigue: a case report

A1

Significant fatigue, diminished energy, or increased need to rest, disproportionate to any recent change in activity level

A2

Complaints of generalised weakness or limb heaviness

A3

Diminished concentration or attention

A4

Decreased motivation or interest to engage in usual activities

A5

Insomnia or hypersomnia

A6

Experience of sleep as unrefreshing or nonrestorative

A7

Perceived need to struggle to overcome inactivity

A8

Marked emotional reactivity (e.g., sadness, frustration, or irritability) to feeling fatigued

A9

Difficulty completing daily tasks attributed to feeling fatigued

A10

Perceived problems with short-term memory

A11

Postexertional malaise lasting several hours

B

The symptoms cause clinically significant distress or impairment in social, occupational, or other important areas of functioning

C

There is evidence from the history, physical examination or laboratory findings that the symptoms are a consequence of cancer or cancer therapy

D

The symptoms are not primarily a consequence of comorbid psychiatric disorders such as major depression, somatization disorder, somatoform disorder, or delirium

  1. CRF is diagnosed when six (or more) of the symptoms above have been present everyday or nearly every day during the same two-week period in the past month, and at least one of the symptoms is significant fatigue (A1) [4, 5].