Table 1 Reagents and results in immunohistochemistry.
Antigens | Antibodies (clone) | Sources | Giant cell sarcomatoid | SCC | TCC |
|---|---|---|---|---|---|
Pancytokeratin | AE1/3 | Dako Corp. Glostrup, Denmark | ++ | +++ | +++ |
Pancytokeratin | CAM5.2 | Becton Dickinson Co. CA, USA | ++ | +++ | +++ |
HMWCK | 34βE12 | Dako | + | + | ++ |
CK5/6 | D5/16 | Dako | + | ++ | ++ |
CK7 | N1626 | Dako | + | + | ++ |
CK8 | 35βH11 | Dako | + | ++ | ++ |
CK14 | LL002 | Novocastra, Newcastle upon type, UK | + | + | ++ |
CK 18 | DC10 | Dako | ++ | +++ | +++ |
CK 19 | RCK 108 | Progen, Heidelberg, Germany | - | + | + |
CK20 | K20.8 | Dako | - | - | ++ |
EMA | E29 | Dako | + | + | ++ |
Chromogranin | DAK-A3 | Dako | - | - | - |
Synaptophysin | Polyconal | Dako | - | - | - |
CD56 | MOC-1 | Dako | - | - | - |
CD68 | KP-1 | Dako | - | - | - |
Melanosome | HMB45 | Dako | - | - | - |
Vimentin | Vim 3B4 | Dako | +++ | - | - |
Desmin | D33 | Dako | - | - | - |
S100 protein | polyclonal | Dako | - | - | - |
ASMA | 1A4 | Dako | - | - | - |
Myoglobin | polyclonal | Dako | - | - | - |
CD34 | NU-4A1 | Nichirei, Tokyo, Japn | - | - | - |
p53 protein | DO-7 | Dako | ++ | ++ | + |
Ki-67 | MIB-I | Dako | 72% | 67% | 32% |