Figure 1

Plotted concentrations of arsenic and copper in blood and urine samples under chelation therapy. Chelating therapy was preceded, three days before, by one session of plasmapheresis. Penicillamine (Pen) was administrated between days 4 and 7, followed by dimercaprol from days 8 to 18. Normal values: arsenic (24 h urine) <100 µg/L; arsenic (blood) <70 µg/L; copper (24 h urine) = 15-60 µg/L; copper (blood) = 0.7-1.5 µg/L.