Disseminated peritoneal hydatidosis following blunt abdominal trauma: A case report
© Shah et al; licensee BioMed Central Ltd. 2008
Received: 16 July 2008
Accepted: 21 August 2008
Published: 21 August 2008
A middle age lady presented with abdominal pain was diagnosed to have multiple peritoneal and hepatic hydatid cysts on CT scan. Retrospectively she was found to have suffered blunt abdominal trauma.
Hydatid cyst disease is a zoonotic disease caused by the larval stage of Echinococcus granulosus (dog tapeworm), E. multilocularis, or E. vogeli . This disease occurs when humans ingest the hexacanth embryos of the dog tape worm. Infestation by hydatid disease in humans most commonly occurs in the liver (55–70%) followed by the lung (18–35%); the two organs can be affected simultaneously in about 5–13% of cases .
Peritoneal hydatidosis is almost always secondary to hepatic disease, although some unusual cases of primary peritoneal hydatidosis have been described. The overall frequency of peritoneal disease in cases of abdominal echinococcus is approximately 13%. Peritoneal involvement is usually undetected unless cysts are large enough to cause symptoms. Most of the cases of peritoneal hydatid disease are secondary to previous surgery for liver hydatidosis. In present case blunt abdominal injury was the probable cause of dissemination. Systemic anaphylaxis is usually associated with cyst rupture and can be predicted by positivity of Casoni reaction.
USG is the first line of screening for abdominal hydatidosis. USG is particularly useful for detection of cystic membrane, septa, and to look for hydatid sand. CT scan best demonstrates cyst wall calcification and cyst infection . Immunoelectrophoresis, enzyme-linked immunosorbent assay (ELISA), latex agglutination and indirect haemagglutination (IHA) test are being carried out for the diagnosis, screening and post-operative follow up for recurrence .
The treatment of choice for localized hydatid cysts in liver or lungs is principally surgical while the therapy for disseminated peritoneal hydatidosis remains medical . Therapy with albendazole or praziquantel remains the mainstay of medical therapy. After medical treatment, the hydatid cysts show gradual reduction in cyst size and number and the follow up is advisable with Ultrasonography or CT scan. In our case despite of sufficient medical treatment the cyst size and number did not reduced and hence surgery remained the final resort. Surgery can be performed with removal of the cyst after sterilizing the cyst with formalin or alcohol. However, pre- and post-operative 1-month courses of albendazole or 2 weeks of praziquantel should be considered in order to sterilize the cyst, decrease the chance of anaphylaxis, decrease the tension in the cyst wall and to reduce the recurrence rate post-operatively . Intra-operatively, the use of hypertonic saline or 0.5% silver nitrate solutions before opening the cavities tends to kill the daughter cysts and therefore prevent further spread or anaphylactic reaction.
Anaphylctic shock occurs when there is prior sensitization. The present case might have been sensitized at the time of rupture of hepatic cyst when she sustained blunt abdominal trauma. Utmost care of preventing the contact of hydatid cyst contents with the body tissues during operation can not avoid the anaphylactic shock. The surgeon should be ready for this catastrophe while operating hydatid cyst especially with the suspicion of prior sensitization.
A written consent was taken from the patient and her father regarding the publishing of this article.
- McManus DA, Smyth JD: Hydatidosis: Changing Concepts in Epidemiology and Speciation. Parasitology Today. 1986, 2: 163-168. 10.1016/0169-4758(86)90147-X.View ArticlePubMedGoogle Scholar
- Saidi F: Treatment of Echinococcal Cysts. Mastery of Surgery. Edited by: Nyhus LM, Baker RJ, Sabiston DC. 1992, London: Little, Brown and Company, 818-37. 2Google Scholar
- Von Sinner WN: New diagnostic signs in hydatid disease; radiography, ultrasound, CT and MRI correlated to pathology. Eur J Radiol. 1991, 12 (2): 150-9. 10.1016/0720-048X(91)90119-G.View ArticlePubMedGoogle Scholar
- Nutman Thomas, Weller Peter: Cestodes. Harrison's Principles of Internal Medicine. Edited by: Isselbacher Kurt J, Braunwald E, Wilson Jean D, Martin Joseeph B, et al. 1994, McGraw-Hill, Inc, 1: 931-3. 13Google Scholar
- World Health Organization: Guidelines for treatment of cystic and alveolar echinococcosis in humans. WHO Informal Working Group on Echinococcosis. Bull World Health Organ. 1996, 74 (3): 231-42.Google Scholar
- Miron D, Kawar B, Lumelsky D, Spiegel R, Horovitz Y: Encysted peritoneal hydatidosis in a child – the effectiveness of pre-operative therapy with a combination of praziquantel and albendazole. Ann Trop Med Parasitol. 2005, 99: 577-82. 10.1179/136485905X51445.View ArticlePubMedGoogle Scholar
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