Multiple associated anomalies in a single patient of duodenal atresia: a case report
© Mirza et al; licensee BioMed Central Ltd. 2008
Received: 16 August 2008
Accepted: 06 October 2008
Published: 06 October 2008
Duodenal atresia is a common cause of intestinal obstruction in neonates. It is associated with other congenital anomalies like Down's syndrome, annular pancreas etc.
We present a case of a two days old male baby presented to us with bilious vomiting since birth. It was associated with Down's syndrome, Annular pancreas and Malrotation.
Duodenal atresia is associated with other congenital anomalies but more than one congenital anomalies in a single patient is very rare.
The duodenum is the most common site of intestinal obstruction accounting for nearly half of all cases . The incidence of duodenal atresia is estimated as 1 in 6000–10000 births . Embryological basis for etiology of duodenal atresia are thought to be due to errors of recanalization . Approximately half of all infants with duodenal atresia or stenosis will also have a congenital anomaly of another organ system .
Duodenal atresia is associated with Down's syndrome (30%), annular pancreas (23%), congenital heart disease (22%), malrotation (20%), oesophageal atresia (8%), others (20%) .
The mainstay of treatment is surgical intervention. Duodenoduodenostomy is most frequently performed operation.
We report a case of duodenal atresia associated with more than one congenital anomalies.
At operation we found duodenal atresia, annular pancreas and malrotaion of gut.
Duodenoduodenostomy was peformed. Recovery of patient was uneventful.
Duodenal atresia is frequently associated with other congenital anomalies but combination of anomalies in a single patient is very rare. This report illustrates a rare setting in which three associated congenital anomalies were present in a single patient of duodenal atresia.
Written informed consent was obtained from the parents for publication of this case report.
We are grateful to Prof. Dr.M Afzal Sheikh, Dr.M.Sharif, Dr.Afzal Sipra, Dr. Shahid Iqbal, Dr.Nasir Mahmood, Dr.Arsalan Qureshi and other colleagues for giving suggestions and comments.
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