Dysphagia caused by a fibrovascular polyp: a case report
© Blacha et al; licensee BioMed Central Ltd. 2008
Received: 10 September 2008
Accepted: 19 November 2008
Published: 19 November 2008
A 73-year old man presented with dysphagia for liquid and solid food. Barium contrast study of the esophagus and esophagoscopy demonstrated a fibrovascular polyp. This, almost 10 cm benign esophageal tumor, was removed surgically by a cervical esophagotomy. A fibrovascular polyp is a rare benign tumor of the esophagus, which, however, may give serious complications as asphyxia resulting from laryngeal obstruction leading to sudden death.
Dysphagia is a serious symptom and it can be caused by malignant process such as esophageal cancer or compression of the esophagus, neurological and motility disorders such as achalasia, or benign disorders like strictures, diverticula or esophagitis. However, seldom dysphagia is caused by a benign polyp, which protrudes in the esophagus.
Macroscopically, an almost 10 cm sausage-shaped mass was removed (Figure 3). Histological examination revealed a polypoid lesion covered by squamous epithelium. The underlying stroma consisted of a mixture of large vascular structures, fibrous connective and myxoid tissue. No signs of inflammation, dysplasia or malignancy were identified. These features match with the diagnosis of a fibrovascular polyp.
Benign tumors of the esophagus account for 20% of the esophageal lesions. 60–80% of the lesions are leiomyomas, typically occurring as intramural lesions in the middle and lower esophagus . The second most common benign esophageal tumors are squamous papillomas. They occur as small finger-like polyps in the lower esophagus. Hemangiomas of the esophagus are rare, but more prevalent than fibrovascular polyps . Fibrovascular polyps, or allegedly polypoid fibroma, myoma, fibrolipoma, pedunculated lipoma, fibroepithelial polyp or lipoma of the hypopharynx, account for 1–2% of all esophageal tumors . They are most commonly found in males around the age of 50 years .
Fibrovascular polyps are postulated to originate from two areas of lower resistance in the pharyngeal musculature. One is between the superior and inferior cricopharyngeal muscle (Killian's dehiscence), the other is between the inferior cricopharyngeus muscle and the proximal end of the esophagus (the Laimer's triangle). In these areas, nodular submucosal thickenings of submucosal folds may evaginate through the mucosa. Due to peristaltic activity and traction the evagination increases to a giant polyp up to 25 cm in length . Histopathologically, the polyp exists of fibrovascular connective tissue with fatty cells and is covered with squamous epithelium .
Since the polyp is slowly growing, it may become symptomatic after years. The most common complaints include dysphagia and sensation of a mass. Other complaints are retrosternal or epigastric discomfort, odynophagia, vomiting, weight loss and respiratory symptoms such as persisting cough and shortness of breath. The most distinctive feature of a fibrovascular polyp is regurgitation into the mouth . A feared complication is asphyxia and laryngeal obstruction by the polyp causing sudden death [5, 6]. When the polyp twists, it leads to hemorrhage and necrosis of the lesion. Hematemesis or occult gastrointestinal bleeding leading to anemia is probably related to ulceration of the tip of the polyp due to peptic digestion when it protrudes through the cardia into the stomach. Although unusual, the polyp can show malignant degeneration .
Fibrovascular polyps are visualized by different modalities such as barium contrast studies, esophagoscopy, endosonography, CT scanning and MRI. A barium contrast study typically demonstrates a significant intraluminal-filling defect within the widened esophagus, from the upper esophagus till the gastro-esophageal junction, while on swallowing the defect moves along. The polyp is shown by endoscopy, however, since it is covered with normal mucosa, it is easily missed. Chest x-ray shows a posterior mediastinal mass. CT scanning, MRI or ultrasonography can be useful to diagnose the fibrovascular polyp. In particular, MRI might be decisive in the choice of treatment by demonstrating the composition of the polyp. If the mass consists predominantly of fat with a minimal blood supply, the risk of bleeding during an endoscopic treatment is small. In case the polyp is rich of vascular structures, endoscopic resection can be troublesome due to uncontrollable bleeding . Therefore, the first choice of therapy is surgical excision, preferable by a left-sided cervical approach. In case of a large sized polyp a thoracotomy may be necessary. Possible complications of a cervical polypectomy are (transient) dysphonia, pneumothorax and development of a cervical esophagus fistula . Recurrence of the lesion is only seen when residual tissue is left at the resection site .
A fibrovascular polyp is a seldom-occurring benign tumor of the esophagus causing dysphagia. It is to be removed by surgical excision preventing serious complications such as asphyxia and laryngeal obstruction.
Written informed consent was obtained from the patient for publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal
- Kuo MJ, Yeh HZ, Chen GH, Jan YJ: Diffuse esophageal leiomatosis with a pedunculated polyp. J Gastroenterol. 2004, 39: 1205-09. 10.1007/s00535-004-1473-z.View ArticlePubMedGoogle Scholar
- Drenth JPH, Wobbes Th, Bonenkamp JJ, Nagengast FM: Recurrent esophageal fibrovascular polyps: case history and review of the literature. Dig Dis Sci. 2002, 47: 2598-2604. 10.1023/A:1020592900552.View ArticlePubMedGoogle Scholar
- Borges A, Bikhazi H, Wensel JP: Giant fibrovascular polyp of the oropharynx. Am J Neuroradiol. 1999, 20: 1979-82.PubMedGoogle Scholar
- Lüthen R, Janzik U, Derichs R, Balló H, Ramp U: Giant fibrovascular polyp of the esophagus. Eur J Gastroenterol Hepatol. 2006, 18: 1005-9. 10.1097/01.meg.0000228971.34280.57.View ArticlePubMedGoogle Scholar
- Carrick C, Collins KA, Lee CJ, Prahlow JA, Barnard JJ: Sudden death due to asphyxia by esophageal polyp: two case reports and review of asphyxial deaths. Am J Forensic Med Pathol. 2005, 26: 275-81. 10.1097/01.paf.0000178098.33597.de.View ArticlePubMedGoogle Scholar
- Sargent RL, Hood IC: Asphyxiation caused by giant fibrovascular polyp of the esophagus. Arch Pathol Lab Med. 2006, 130: 725-7.PubMedGoogle Scholar
- Ascenti G, Racchiusa S, Mazziotti S, Bottari M, Scribano E: Giant fibrovascular polyp of the oesophagus: CT and MR findings. Abdom Imaging. 1999, 24: 109-10. 10.1007/s002619900455.View ArticlePubMedGoogle Scholar
- Crema E, Ribeiro LBP, Terra JA, Silva AA: Laparoscopic transhiatal subtotal esophagectomy for the treatment of advanced megaesophagus. Ann Thorac Surg. 2005, 80: 1196-1201. 10.1016/j.athoracsur.2004.10.059.View ArticlePubMedGoogle Scholar
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