Clinical and pathological report of an unusual anterior chamber lesion: A case report
© Najjar et al; licensee BioMed Central Ltd. 2008
Received: 30 June 2008
Accepted: 08 September 2008
Published: 08 September 2008
To describe an unusual anterior chamber lesion found on routine eye examination of a 71 year-old Hispanic gentleman who presented for cataract evaluation. The lesion was biopsied at the time of cataract surgery and its pathology presented.
A 71 year-old Hispanic gentleman presented for routine cataract evaluation. We found an unusual lesion in the anterior chamber of the right eye. The patient underwent uneventful phacoemulsification surgery. The lesion was biopsied at the time of cataract surgery and sent for pathology. Clinical photos and its pathology are presented in this article.
Despite biopsy and several ancillary testings, the nature of this lesion remains unknown. Only long-term follow-up of the left eye might reveal clues as to the origins of this unusual lesion.
We describe an unusual anterior chamber lesion found on routine eye examination of a 71 year-old gentleman who presented for cataract evaluation. The lesion was biopsied at the time of cataract surgery and its pathology presented.
A review of the literature using PubMed has revealed previously reported cases of anterior segment epibulbar choristomas containing brain tissue arising from the cornea [1, 2]. However, in our case, pathology did not reveal any abnormal tissue, and it is unknown whether the patient was born with this lesion or whether it was acquired. Other entities to consider in the differential diagnosis include lesions arising from the iris or ciliary body and extending into the cornea and anterior chamber . However this was not the case as it was ruled out by gonioscopy. Stone et al reported a case of metaplastic squamous epithelial downgrowth occurring after clear corneal cataract surgery . Our patient had not undergone any ocular surgeries prior to his initial visit, and the eye was quiet without any signs of inflammation.
Questions as to the etiology of this lesion remain unanswered. Did this lesion originate in the posterior cornea and then protrude in the anterior chamber, or did it originate in the anterior chamber and got stuck to the posterior cornea? Could it represent some form of hamartomatous proliferation of the posterior stroma, or was it acquired? Only long-term follow-up of the left eye might reveal some clues as to the origins of this unusual anterior chamber lesion.
Written informed consent was obtained from the patient for publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.
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